Saturday 25 June, 2011

Dr.Subhash Mukhopadhyay-The Second Man to create Test Tube Baby

He was born on January 16, 1931 in Hazaribag, Bihar (now in jharkhand), India. He studied and graduated (in 1955) with an honours degree in physiology from the Calcutta National Medical College, which was then affiliated with the prestigious University of Calcutta.He created history when he became the first physician in India (and second in the world after British physicians Patrick Steptoe and Robert Edwards) to perform the In vitro fertilization resulting in a test tube baby "Durga" (alias Kanupriya Agarwal) on October 3, 1978.Facing social ostracization, bureaucratic negligence, reprimand and insult instead of recognition from the West Bengal government and refusal of the Government of India to allow him to attend international conferences, he committed suicide in his Calcutta residence on 19 June 1981.His feat has been given belated recognition as the Indian physician who in 1986 was "officially" regarded as being the first doctor to perform in-vitro fertilization in India.
18 November 1978. An ‘expert committee’ was appointed by the Government of West Bengal under the medical association to decide over the fate of a convict named Dr. Subhas Mukhopahyay. His charges are, one, he claims to be the architect of first human test tube baby named Durga (3 October 1978). Secondly, he denounced the report to the media before being cleared off by the Government bureaucrats. Thirdly, he made this impossible possible with few general apparatus and a refrigerator in his small southern avenue flat while others cannot even think of it, although, having all the expensive resources in their hand. (in this research Mukhopadhyay was assisted by Sumit Mukherjee and S.K. Bhattacharya.). Fourth and most important allegation, he never let his head down by the Government Bureaucrats and his straightforwardness always attracted jealousy out of his peers. The committee was presided over by a Radio physicist and it was composed of a gynecologist, a psychologist, a physicist and a neurologist. None of them were having any knowledge about modern reproductive technology. “Where did you keep these embryos?” Mukhopahdhyay said “in sealed ampules.” Then he asked again “How did you seal an ampule?” Speechless Mukhopadhyay could only utter “pardon?” From here started a questioning and counter questioning session which need not to be mentioned was utterly meaningless. “Oh! Embryos do not die while sealing?” there were people who never saw embryos in the entire span of their lifetime.
The Committee put forward its final verdict, “Everything that Dr. Mukhopadhyay claims is bogus.”
Only 67 days earlier, on 25 July 1978, world’s first human test tube baby Louise Joy Brown was born at Oldham General Hospital in England. Architects were Robert Edward and Patrick Steptoe. In their procedure they collected Ovum By using Laparoscope. At first they observed the evolution and development of the Ovum for a long span of time and then collected it through a small incision. Ovum thus collected is then fertilized by sperm on a small disc. When it forms into an embryo scientists placed it into the womb. But Mukhopadhyay without using laparoscope collected ovum by performing a small operation in the vagina. He increased the number of ovum collected by using a hormone and developed embryo. Lastly, he placed it in the womb.
Thanks to his peers and Government bureaucrats he ultimately handed with a punishment. He had been transferred to ophthalmic department which sealed his prospect to work on hormones.What is more ridiculous is that after his death, in 1983, one by one three scientists Howard Jones, Gleichar and Trounson (Australia) in three separate research claimed the invention of Human test tube baby. All these three research were already successfully accomplished by Mukhopadhyay long before their time. One of these scientists even found his research published in famous Journal “Nature”.
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